CD8+T Lymphocytes Control Murine Cytomegalovirus Replication in the Central Nervous System of Newborn Animals
نویسندگان
چکیده
منابع مشابه
CD8+ T lymphocytes control murine cytomegalovirus replication in the central nervous system of newborn animals.
Human CMV infection of the neonatal CNS results in long-term neurologic sequelae. To define the pathogenesis of fetal human CMV CNS infections, we investigated mechanisms of virus clearance from the CNS of neonatal BALB/c mice infected with murine CMV (MCMV). Virus titers peaked in the CNS between postnatal days 10-14 and infectious virus was undetectable by postnatal day 21. Congruent with vir...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2008
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.181.3.2111